Edward M Schwarz Selected Research

Osteoarthritis

1/2019	Attenuated Joint Tissue Damage Associated With Improved Synovial Lymphatic Function Following Treatment With Bortezomib in a Mouse Model of Experimental Posttraumatic Osteoarthritis.
9/2011	Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis.
8/2010	Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring transforming growth factor beta-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis.
1/2006	Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation.
11/2003	Articular cartilage biology.
1/2002	Volumetric computerized tomography as a measurement of periprosthetic acetabular osteolysis and its correlation with wear.

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Edward M Schwarz Research Topics

Disease

39	Arthritis (Polyarthritis) 01/2023 - 05/2002
37	Infections 12/2023 - 08/2002
25	Osteolysis 08/2022 - 01/2002
24	Bone Resorption 01/2022 - 02/2002
22	Osteomyelitis 11/2023 - 03/2010
20	Rheumatoid Arthritis 10/2022 - 05/2002
19	Neoplasms (Cancer) 01/2024 - 01/2002
18	Inflammation (Inflammations) 01/2022 - 03/2002
8	Synovitis 01/2023 - 01/2013
8	Hypertrophy 10/2020 - 06/2002
8	Neoplasm Metastasis (Metastasis) 09/2015 - 04/2002
7	Osteoporosis 12/2014 - 08/2008
6	Osteoarthritis 01/2019 - 01/2002
5	Prostatic Neoplasms (Prostate Cancer) 02/2012 - 10/2002
4	Persistent Infection 01/2021 - 10/2018
3	Joint Diseases (Joint Disease) 01/2023 - 09/2011
3	Abscess 08/2022 - 01/2017
3	Metabolic Bone Diseases (Osteopenia) 01/2022 - 07/2003
3	Communicable Diseases (Infectious Diseases) 01/2021 - 09/2015
3	Interstitial Lung Diseases (Interstitial Lung Disease) 12/2019 - 01/2019
3	Wounds and Injuries (Trauma) 01/2019 - 03/2005
3	Reinfection 01/2019 - 01/2018
3	Cicatrix (Scar) 02/2015 - 06/2009
3	Psoriatic Arthritis 01/2014 - 01/2003
3	Breast Neoplasms (Breast Cancer) 02/2012 - 10/2002
2	Sepsis (Septicemia) 11/2023 - 01/2021
2	Disease Progression 01/2023 - 10/2020
2	Bacterial Infections (Bacterial Infection) 08/2022 - 01/2021
2	Coinfection 10/2021 - 01/2021
2	Diabetic Foot 01/2019 - 12/2018
2	Fibrosis (Cirrhosis) 09/2017 - 03/2013
2	Arthralgia (Joint Pain) 01/2017 - 01/2016
2	Hypersensitivity (Allergy) 01/2017 - 01/2006
2	Obesity 01/2017 - 06/2015
2	Pain (Aches) 01/2016 - 01/2002
2	Renal Cell Carcinoma (Grawitz Tumor) 09/2015 - 02/2012
2	Tendon Injuries 02/2015 - 01/2012
2	Femoral Fractures (Femoral Fracture) 02/2013 - 04/2011
2	Intervertebral Disc Degeneration 08/2012 - 09/2011

Drug/Important Bio-Agent (IBA)

37	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2023 - 05/2002
19	Anti-Bacterial Agents (Antibiotics)IBA 12/2023 - 03/2015
15	CytokinesIBA 10/2022 - 03/2002
13	Biomarkers (Surrogate Marker)IBA 01/2022 - 07/2008
10	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2002
8	RANK LigandIBA 01/2021 - 03/2002
8	OsteoprotegerinIBA 03/2010 - 03/2002
6	Diphosphonates (Bisphosphonates)IBA 10/2023 - 10/2002
6	Immunoglobulin G (IgG)IBA 01/2023 - 04/2011
6	LigandsIBA 10/2022 - 03/2002
5	Vancomycin FDA LinkGeneric 10/2023 - 03/2015
5	Indocyanine Green (Cardio-Green)FDA LinkGeneric 01/2023 - 07/2010
5	AntigensIBA 03/2021 - 11/2013
5	Hexosaminidases (Hexosaminidase)IBA 11/2020 - 04/2011
5	Monoclonal AntibodiesIBA 01/2018 - 04/2011
5	Transforming Growth Factor beta (TGF-beta)IBA 08/2010 - 05/2004
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 10/2022 - 05/2008
4	ChemokinesIBA 10/2022 - 12/2005
4	AntibodiesIBA 01/2022 - 12/2018
4	Polymethyl Methacrylate (Sol)IBA 02/2019 - 08/2009
4	Anabolic AgentsIBA 09/2017 - 01/2008
4	Teriparatide (Parathar)FDA Link 03/2016 - 09/2008
4	Parathyroid Hormone (Parathormone)IBA 12/2014 - 09/2011
4	TitaniumIBA 10/2009 - 02/2002
4	NF-kappa B (NF-kB)IBA 06/2007 - 04/2005
4	Transcription Factors (Transcription Factor)IBA 07/2006 - 10/2003
4	Collagen Type XIBA 07/2006 - 06/2002
3	sitafloxacinIBA 10/2023 - 02/2019
3	Vascular Endothelial Growth Factor CIBA 01/2023 - 05/2008
3	VaccinesIBA 01/2021 - 10/2014
3	EnzymesIBA 01/2021 - 04/2005
3	Bone Cements (Bone Glue)IBA 01/2021 - 10/2004
3	C-Reactive ProteinIBA 01/2019 - 11/2013
3	ultra-high molecular weight polyethylene (UHMWPE)IBA 01/2016 - 09/2002
3	Messenger RNA (mRNA)IBA 09/2015 - 09/2004
3	Matrix Metalloproteinases (MMPs)IBA 02/2015 - 06/2009
3	GlucocorticoidsIBA 11/2012 - 11/2003
3	Alendronate (Alendronate Sodium)FDA LinkGeneric 03/2010 - 10/2003
3	Dinoprostone (PGE2)FDA Link 10/2009 - 01/2002
3	Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)IBA 06/2007 - 02/2002
2	LuciferasesIBA 01/2024 - 09/2023
2	Interleukin-27 (Interleukin 27)IBA 08/2022 - 01/2021
2	Anti-Infective Agents (Microbicides)IBA 01/2021 - 10/2018
2	Gentamicins (Gentamicin)FDA LinkGeneric 02/2019 - 03/2010
2	Rifampin (Rifampicin)FDA LinkGeneric 02/2019 - 01/2017
2	MetalsIBA 01/2017 - 01/2006
2	AntioxidantsIBA 01/2016 - 05/2013
2	Tumor Necrosis Factor InhibitorsIBA 08/2015 - 11/2003

Therapy/Procedure

46	Therapeutics 12/2023 - 08/2003
6	Debridement 10/2023 - 03/2015
6	Arthroplasty 01/2017 - 02/2002
4	Surgical Amputation (Amputations) 03/2021 - 01/2019
4	Replacement Arthroplasty 09/2015 - 05/2002
4	Prostheses and Implants (Prosthesis) 12/2014 - 01/2002
4	Drug Therapy (Chemotherapy) 04/2011 - 08/2002
3	Immunotherapy 01/2021 - 01/2018
3	Reoperation 01/2018 - 04/2011
2	Intramuscular Injections 08/2022 - 08/2002
2	Salvage Therapy 01/2019 - 12/2018
2	Orthopedic Procedures 01/2019 - 01/2019
2	Hip Replacement Arthroplasty (Total Hip Replacement) 01/2016 - 11/2003